ÖZET

Amaç:

Bu çalışmanın amacı, 1990 American College of Rheumatology (ACR) FM, 2010 ACR FM ve AAPT 2018 FM kriterlerine göre FM prevalansını hesaplamak ve karşılaştırmaktır. İkinci amacı ise axSpA’ya eşlik eden fibromiyaljinin hastalık aktivitesine, yaşam kalitesine, fonksiyonalite ve entezopatiye etkisini ortaya çıkarmaktır.

Gereç ve Yöntem:

Bu çalışma tek merkezli kesitsel çalışmadır. ASAS kriterlerine göre axSpA tanısı almış 86 (61 nr-axSpA, 25 AS) hasta ile gerçekleştirilmiştir. Demografik karakterleri, hastalık süresi, HLA B27 pozitifliği, eritrosit sedimentasyon hızı, C-reaktif protein (CRP), BASDAI, BASFI, BASMI, MASES, ASDAS-CRP, ASDAS-ESR, ASQoL ve FIQ ölçülmüştür. Hastalara 1990 ACR FM, 2010 ACR FM ve AAPT 2018 FM kriterlerine FM prevalansı hesaplanmıştır.

Bulgular:

Hastaların 1990 ACR ,2010 ACR FM ve AAPT 2018 FM kriterlerine göre FM prevalansı sırasıyla 7 (%8,1), 36 (%41,9), 33 (%38,4) olarak bulunmuştur. 1990 ACR FM kriteri BASFI (r=0,375, p=0,001), BASDAI (r=0,250, p=0,020), MASES (r=0,228, p=0,035), ASQol (r=0,264, p=0,014) ve FIQ (r=0,321, p=0,003) ile koraledir. 2010 ACR FM kriteri BASFI, BASMI, BASDAI, ASDAS-ESR, ASDAS-CRP, MASES, ASQoL ve FIQ ile koraledir. (r=0,267-0,666, p=0,001-0,013). AAPT 2018 FM kriteri ise BASDAI (r=0,282, p=0,008) ve FIQ (r=0,263, p=0,014) ile koraledir.

Sonuç:

axSpA hastalarda, FM varlığı yaşam kalitesini, hastalık aktivitesini ve fonksiyonaliteyi olumsuz olarak etkiler. AAPT 2018 FM kriterleri, günlük pratikte FM tanısını koymak için kullanılabilir. axSpA’ya eşlik eden fibromiyalji, hastalığın tedavisinin yönetilmesinde dikkate alınmalıdır.

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Aksiyel Spondiloartropatide Fibromiyalji Prevalansının ACR 1990 FM, ACR 2010 FM, AAPT 2018 FM Kriterlerine Göre Karşılaştırılması ve Eşlik Eden Fibromiyaljinin Hastalık Aktivitesi, Yaşam Kalitesi, Fonsiyonalite ve Entezopatiye Etkisi

ÖZET

References