ABSTRACT

Peutz-Jeghers syndrome is an autosomal dominantly inherited disorder which is characterized with hyperpigmented skin and mucosa lesions, intestinal and extraintestinal multiple hamarto-matous polips. Intestinal polips may cause iron deficiency anemia due to gastrointestinal ble-eding and intestinal obstruction due to intusseption. Gastrointestinal and extragastrointestinal malignancy risk is remarkably increased in patients with Peutz-Jeghers syndrome. Laparatomy was performed to a 48-year-old man because of recurrent intusseptions. The reason of intussu-seption was found as hamartomatous polyp in the jejenum and the patient was diagnosed as adult Peutz-Jeghers syndrome. We present our case to remind that Peutz-Jeghers syndrome is a precancerous syndrome, can be seen at adult and all the patients should be followed up to avoid multiple laparatomies due to intestinal polips.

Keywords: Peutz-Jeghers Syndrome, Hamartomatous Polyp, Intussuseption, Follow-up