Drug-Drug Interaction Management in Hepatitis C Treatment
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Case Report
P: 174-176
August 2018

Drug-Drug Interaction Management in Hepatitis C Treatment

J Ankara Univ Fac Med 2018;71(2):174-176
1. Ankara Üniversitesi Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Ankara, Türkiye
2. Dicle Üniversitesi Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Diyarbakır, Türkiye
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Received Date: 26.03.2018
Accepted Date: 25.07.2018
Publish Date: 10.10.2018
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ABSTRACT

“Direct acting antivirals” cure over 99% in the course of the disease as a recent breakthrough treatment method in hepatitis C treatment. Possible drug-drug interactions should not be overlooked. In this case report we aimed to share how we managed the interaction in a patient who was planned to use sofosbuvir-ledipasvir. The use of direct antiviral drugs is a very important point in Hepatitis C treatment. A good patient history and a multidisciplinary approach are necessary for the interaction of drugs. These are necessary for successful and safe treatment of hepatitis C.

Keywords: Antiviral Treatment, Hepatitis C, Drug-drug Interactions

References

1
Initial Treatment of HCV Infection | HCV Guidance [Internet]. [cited 2018 Mar 12]. Available from: https://www.hcvguidelines.org/treatment-naive
2
Aygen B, Üniversitesi E, Fakültesi T, et al. Kronik Hepatit C Virusu İnfeksiyonunun Yönetimi: Türk Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Derneği Viral Hepatit Çalışma Grubu Uzlaşı Raporu-2017 Güncellemesi. [cited 2018 Mar 12]; Available from: http://www.klimikdergisi.org/sayilar/104/buyuk/2-362.pdf
3
Carbamazepine Level: Reference Range, Interpretation, Collection and Panels [Internet]. [cited 2018 Mar 12]. Available from: https://emedicine.medscape.com/article/2089796-overview
4
Aşcı Songül Özkula Süleyman Demirel Üniversitesi H, Fakultesi T, Yazışma Adresi I, Doç Halil Aşcı Y. Terapötik indeksi dar olan ilaçlarda etkileşimler Drug interactions with narrow therapeutic index. [cited 2018 Mar 12]; Available from: http://dergipark.gov.tr/download/article-file/227753
5
Liverpool HEP Interactions [Internet]. [cited 2018 Mar 12]. Available from: https://www.hep-druginteractions.org/
6
Talavera Pons S, Boyer A, Lamblin G, et al. Managing drug-drug interactions with new direct-acting antiviral agents in chronic hepatitis C. Br J Clin Pharmacol [Internet]. 2017 Feb 1 [cited 2018 Mar 12];83(2):269–93. Available from: http://doi.wiley.com/10.1111/bcp.13095
7
Odds FC. Synergy, antagonism, and what the chequerboard puts between them. J Antimicrob Chemother [Internet]. 2003 Jun 12 [cited 2018 Mar 21];52(1):1–1. Available from: https://academic.oup.com/jac/article-lookup/doi/10.1093/jac/dkg301
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