Decision for Surgery of Focal Nodular Hyperplasia: Single-Center Experience of 17 Adult Cases
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Case Series
P: 468-471
September 2022

Decision for Surgery of Focal Nodular Hyperplasia: Single-Center Experience of 17 Adult Cases

J Ankara Univ Fac Med 2022;75(3):468-471
1. Ankara Üniversitesi Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Ankara, Türkiye
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Received Date: 02.07.2022
Accepted Date: 18.07.2022
Publish Date: 18.10.2022
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ABSTRACT

Surgery is rarely a necessity for the removal of focal nodular hyperplasia (FNH) lesions. Diagnostic challenges and symptomatic lesions are common indications for surgery. This study was conducted for the purposes of analyzing the indications and results of liver surgeries, revealing FNH in further examinations from specimens sent to pathology. The patients that were operated for liver lesions revealed as FNH at pathological examinations at Ankara University Hospitals between October 2009 and March 2018 were included in this study. Twelve of the patients had some abdominal symptoms, with the remaining four having no reported symptoms. All patients were subjected to at least one imaging modality from computed tomography, ultrasonography or magnetic resonance imaging. Only three patients were diagnosed with certain FNH and were also symptomatic. No jaundice was observed in the group before surgery. Only one patient demonstrated mildly elevated preoperative liver enzyme levels. All patients underwent several types of hepatectomies except for two patients undergoing additional procedures such as pancreatoduodenectomy and cholecystectomy. Only three of the patients had postoperative complications including intraabdominal abscess, biliary leak and pulmonary embolism. No mortality occurred among the group. Surgery is rarely a necessity in the cases of FNH. However, surgical approach is generally preferred when the lesion is suspected to be a lesion other than FNH.

Keywords: Focal Nodular Hyperplasia, Premalignant Lesion, Benign Disease, Hepatectomy

References

1
Nahm CB, Ng K, Lockie P, et al. Focal nodular hyperplasia—a review of myths and truths. J Gastrointest Surg. 2011;15:2275-2283.
2
Perrakis A, Demir R, Müller V, et al. Management of the focal nodular hyperplasia of the liver: evaluation of the surgical treatment comparing with observation only. Am J Surg. 2012;204:689-696.
3
Chen MF. Hepatic resection for benign tumours of the liver. J Gastroenterol Hepatol. 2000;15:587-592.
4
Jung JM, Hwang S, Kim KH, et al. Surgical indications for focal nodular hyperplasia of the liver: Single-center experience of 48 adult cases. Ann Hepatobiliary Pancreat Surg. 2019;23:8-12.
5
Nguyen BN, Fléjou JF, Terris B, et al. Focal nodular hyperplasia of the liver: a comprehensive pathologic study of 305 lesions and recognition of new histologic forms. Am J Surg Pathol. 1999;23:1441-1454.
6
Vilgrain V. Focal nodular hyperplasia. Eur J Radiol. 2006;58:236-245.
7
Navarro AP, Gomez D, Lamb CM, et al. Focal nodular hyperplasia: a review of current indications for and outcomes of hepatic resection. HPB (Oxford). 2014;16:503-511.
8
Bonney GK, Gomez D, Al-Mukhtar A, et al. Indication for treatment and long-term outcome of focal nodular hyperplasia. HPB (Oxford). 2007;9:368-372.
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