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Evaluation of the Children with Hypoparathyroidism and Pseudohypoparathyroidism Presenting to an Endocrinology Outpatient Clinic
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Research Article
VOLUME: 71 ISSUE: 3
P: 212-216
December 2018

Evaluation of the Children with Hypoparathyroidism and Pseudohypoparathyroidism Presenting to an Endocrinology Outpatient Clinic

J Ankara Univ Fac Med 2018;71(3):212-216
DOI: 10.4274/atfm.43043
Pınar Kocaay
Eda Mengen
1. Ankara Çocuk Hematolojisi Onkoloji Eğitim ve Araştırma Hastanesi, Çocuk Endokrinolojisi Kliniği, Ankara, Türkiye
No information available.
No information available
Received Date: 04.10.2018
Accepted Date: 05.11.2018
Publish Date: 26.03.2019
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ABSTRACT

Objectives:

The epidemiology of hypoparathyroidism (HP) is largely unknown. We aimed to identify a clinical profile, prevalence, laboratory findings, etiologies of hypoparathyroidism, and pseudohypoparathyroidism.

Materials and Methods:

Patients with HP and PHP were identified in electronic hospital registries. We noted patient’s laboratory and clinical findings, etiology, renal ultrasonography, and treatment results.

Results:

Twenty-six patients were identified, of which 16 were female and 10 were male. Mean age was 8.06 years and average time of the disease was 3.9 years. The most frequent etiologies were primary hypoparathyroidism (39%), the other etiologies were PHP (35%), DiGeorge syndrome (9%), postsurgical (9%), autoimmune polyglandular syndrome (4%), and thalassemia major (4%). All patients were treated with active vitamin D.

Conclusion:

Understanding the etiology, diagnosis, and symptoms of hypoparathyroidism may help to improve quality of life and long-term disease outcomes. However, further research is necessary to unravel the causes of idiopathic HP and genetic studies should be easier.

Keywords: Epidemiology, Hypoparathyroidism, Pseudohypoparathyroidism

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