Antibiotic Preference in Interventions Frequently Performed by Pediatric Surgeons and Pediatric Urology Doctors in Türkiye
Research Article
P: 75-80
March 2024

Antibiotic Preference in Interventions Frequently Performed by Pediatric Surgeons and Pediatric Urology Doctors in Türkiye

J Ankara Univ Fac Med 2024;77(1):75-80
1. Ankara Üniversitesi Tıp Fakültesi, Çocuk Cerrahisi Anabilim Dalı, Çocuk Ürolojisi Bilim Dalı, Ankara, Türkiye
2. Ankara Üniversitesi Tıp Fakültesi, Çocuk Cerrahisi Anabilim Dalı, Ankara, Türkiye
No information available.
No information available
Received Date: 02.06.2023
Accepted Date: 15.02.2024
Publish Date: 05.04.2024



The practices regarding the use of antibiotics in common pediatric urology procedures are not clear. Therefore, our practical approaches may vary. This survey aimed to evaluate the antibiotic preferences of surgeons in Turkey in urological procedures commonly performed by pediatric surgeons and pediatric urologists.

Materials and Methods:

Ethical approval was obtained from the local ethics committee on 21.11.2022, with approval number I10-626-22. The survey questions, prepared using Google Forms, were sent via email to pediatric surgery and pediatric urology specialists. The study was completed by 40 surgeons.


90% of the participants were pediatric surgery specialists, and 40% had over 16 years of experience. 40% of the participants worked in university hospitals. The rate of antibiotic use was determined to be 80% before and 90% after surgery in distal hypospadias repairs, and 85% before and 97.5% after surgery in proximal hypospadias repairs. When asked about the selected antibiotic types, first and second-generation cephalosporins were most commonly preferred for hypospadias patients. In pyeloplasty, antibiotic use was 95%, and in patients who underwent laparoscopic exploration for an undescended testicle, it was 57.5%. Inguinal approaches for hernia or hydrocele repairs had a 30% antibiotic use rate, and endourological procedures had a rate of 62.5%. The most commonly preferred antibiotic in patients undergoing bladder augmentation was third-generation cephalosporins (51.3%), followed by aminoglycosides (28.2%). Multiple drug use was most pronounced in bladder augmentation cases.


Similar to the global practice, there is no consensus among pediatric urologists in Turkey regarding the use of prophylactic antibiotics before or after surgery. In order to establish standardized approaches, evidence-based, randomized controlled studies involving large patient groups are needed to develop clear guidelines.

Keywords: Antibiotics, pediatric urology, surgery, prophylaxis


Kim JK, Chua ME, Ming JM, et al. Practice variation on use of antibiotics: An international survey among pediatric urologists. J Pediatr Urol. 2018;14:520-524.
Hsieh MH, Wildenfels P, Gonzales ET Jr. Surgical antibiotic practices among pediatric urologists in the United States. J Pediatr Urol. 2011;7:192-197.
Çelen MK. Antibiotic usage and surgical prophylaxis in pediatric urology. Çocuk Cerrahisi Dergisi. 2016;30:80-84.
Soyer T. Cerrahi alan infeksiyon tanımlarında yenilikler ve profilakside güncel uygulamalar. ANKEM Derg. 2014; 28:156-161.
Esposito S, Rigotti E, Argentiero A, et al. Antimicrobial Prophylaxis for Urologic Procedures in Paediatric Patients: A RAND/UCLA Appropriateness Method Consensus Study in Italy. Antibiotics (Basel). 2022;11:296.
Aslan E, Özvatan TŞ, Özer D, et al. Bir üniversite hastanesinde cerrahi profilaksi uygulamalarının değerlendirilmesi. Uludağ Üniversitesi Tıp Fakültesi Dergisi. 2012;38:7-11.
Cherry J, Kaplan SL, Demmler-Harrison GJ, et al. Feigin and Cherry’s Textbook of Pediatric Infectious Diseases E-Book: 2-Volume Set. Elsevier Health Sciences; 2013.
Edlin RS, Copp HL. Antibiotic resistance in pediatric urology. Ther Adv Urol. 2014;6:54-61.
Turan H. Cerrahi antimikrobiyal profilakside güncel öneriler. Klimik Dergisi. 2015;28:2-10.
Bratzler DW, Houck PM; Surgical Infection Prevention Guideline Writers Workgroup. Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project. Am J Surg. 2005;189:395-404.
T.C. Sağlık Bakanlığı. Cerrahi Profilaksi Rehberi.
Rensing AJ, Whittam BM, Chan KH, et al. Is surgical antibiotic prophylaxis necessary for pediatric orchiopexy? J Pediatr Urol. 2018;14:261.e1-261.e7.
Cai T, Verze P, Brugnolli A, et al. Adherence to european association of urology guidelines on prophylactic antibiotics: an ımportant step in antimicrobial stewardship. Eur Urol. 2016;69:276-283.
Laxenaire MC. Epidemiology of anesthetic anaphylactoid reactions. Fourth multicenter survey (July 1994-December 1996). Ann Fr Anesth Reanim. 1999;18:796-809.
Lee CW, Castells MC. Perioperative anaphylaxis to cefazolin. Allergy Asthma Proc. 2004;25:23-26.
Snyder E, Mohan C, Michael J, et al. Inclusion of surgical antibiotic regimens in pediatric urology publications: A systematic review. J Pediatr Urol. 2020;16:595.e1-595.e7.
Chua ME, Kim JK, Rivera KC, et al. The use of postoperative prophylactic antibiotics in stented distal hypospadias repair: a systematic review and meta-analysis. J Pediatr Urol. 2019;15:138-148.
Glaser AP, Rosoklija I, Johnson EK, et al. Prophylactic antibiotic use in pediatric patients undergoing urinary tract catheterization: a survey of members of the Society for Pediatric Urology. BMC Urol. 2017;17:76.
Ferroni MC, Lyon TD, Rycyna KJ, et al. The role of prophylactic antibiotics after minimally invasive pyeloplasty with ureteral stent placement in children. Urology. 2016;89:107-111.
Vidovic S, Hayes T, Fowke J, et al. Pyeloplasty with ureteral stent placement in children: Do prophylactic antibiotics serve a purpose? J Pediatr Urol. 2022;18:804-811.
Ellett J, Prasad MM, Purves JT, et al. Post-surgical infections and perioperative antibiotics usage in pediatric genitourinary procedures. J Pediatr Urol. 2015;11:358.e1-6.
Vaze D, Samujh R, Narasimha Rao KL. Risk of surgical site infection in paediatric herniotomies without any prophylactic antibiotics: A preliminary experience. Afr J Paediatr Surg. 2014;11:158-161.
Schnabel MJ, Wagenlehner FME, Schneidewind L. Perioperative antibiotic prophylaxis for stone therapy. Curr Opin Urol. 2019;29:89-95.
2024 ©️ Galenos Publishing House