Analysis of Patients with Intrathoracic Placement Schwannoma Pathological Diagnosis, Single Center Experience
PDF
Cite
Share
Request
Research Article
P: 135-138
August 2020

Analysis of Patients with Intrathoracic Placement Schwannoma Pathological Diagnosis, Single Center Experience

J Ankara Univ Fac Med 2020;73(2):135-138
1. Ankara Üniversitesi Tıp Fakültesi, Göğüs Cerrahisi Anabilim Dalı, Ankara, Türkiye
No information available.
No information available
Received Date: 27.05.2020
Accepted Date: 29.05.2020
Publish Date: 21.07.2020
PDF
Cite
Share
Request

ABSTRACT

Objectives:

The origin of neurilemmoma is Schwann cells and it is the most frequent subgroup of neurogenic tumors. It is often detected in the 3rd-5th decades. The region is located in the posterior mediastinum. Recurrence rates are very low when surgically resected. In this study, this type of tumor resected in our clinic was analyzed and evaluated with the literature.

Materials and Methods:

Twenty-five patients diagnosed with Schwannoma resected between January 2008 and January 2018 in Ankara University Faculty of Medicine, Department of Thoracic Surgery were retrospectively reviewed. All preoperative patients were evaluated by thoracic computed tomography. In case of suspicion of invasion into the spinal canal, magnetic resonance imaging was used.

Results:

Of all the patients included in the study, 14 (56%) were male and 11 (44%) were female. The mean age was 47±12.6 (31-66) years. The main symptom in the patients was back pain. It was determined that the lesions were frequently located in the paravertebral sulcus. 56% of Schwannoma masses were observed in the right and 44% in the left hemithorax. For resection, 18 patients underwent muscle sparing thoracotomy, six patients underwent video-assisted thoracoscopic surgery, and one patient underwent a median sternotomy procedure.

Conclusion:

The most common type of neurogenic tumors originating from neural cells is neurilemmomas originating from Schwann cells. It is generally located in the posterior mediastinum. They are asymptomatic between the rates of 40% and 60%. In our patients, the rate of symptomatic patients was higher. Recurrence is very low in patients undergoing resection in Schwannoma.

Keywords:
Neurogenic Tumor
Thoracic Surgery
Resection

References

1
Ida CM, Scheithauer BW, Yapıcıer Ö, et al. Primary schwannoma of the bone: A clinicopathologic and radiologic study of 17 cases. Am J Surg Pathol. 2011;35:989-997.
2
Kurtkaya-Yapicier Ö, Scheithauer BW, Woodruff JM, et al. Schwannoma with rhabdomyoblastic differentiation: A unique variant of Malignant Triton Tumor. 2003;27:848-853.
3
Meis-Kindblom JM, Enzinger FM. Plexiform malignant peripheral nerve sheath tumor of infancy and childhood. Am J Surg Pathol. 1994;18:479-485.
4
Miettinen M, Shekitka KM, Sobin LH. Schwannomas in the Colon and Rectum. A Clinicopathologic and Immunohistochemical Study of 20 Cases. 2001;25:846-855.
5
Topçu S, Alper A, Gülhan E, et al. Neurogenic tumours of the mediastinum: a report of 60 cases. Can Respir J. 2000;7:261-265.
6
Yamaguchi M, Yoshino I, Fukuyama S, et al. Surgical treatment of neurogenic tumors of the chest. Ann Thorac Cardiovasc Surg. 2004;10:148-151.
7
Strollo DC, Rosado-de-Christenson ML, Jett JR. Primary mediastinal tumors: part II. Tumors of the middle and posterior mediastinum. Chest. 1997;112:1344-1357.
8
Endo S, Murayama F, Otani S, et al. Alternative surgical approaches for apical neurinomas: a thoracoscopic approach. Ann Thorac Surg. 2005;80:295-298.
9
Ohtsuka T, Nomori H, Naruke T, et al. Intrapulmonary schwannoma. Jpn J Thorac Cardiovasc Surg. 2005;53:154-156.
10
Lin YF, Hsi SC, Chang JL, et al. Intrapulmonary psammomatous melanotic schwannoma. J Thorac Cardiovasc Surg. 2009;137:25-27.
11
Rammos KS, Foroulis CN, Zaramboukas TK, et al. Schwannoma of the vagus nerve, a rare middle mediastinal neurogenic tumor: case report. J Cardiothorac Surg. 2009;4:68.
12
Stouffer CW, Allan RW, Shillingford MS, et al. Endobronchial schwannoma presenting with bronchial obstruction. Interact Cardiovasc Thorac Surg. 2010;10:133-134.
13
Kasahara K, Fukuoka K, Konishi M, et al. Two cases of endobronchial neurilemmoma and review of the literature in Japan. Intern Med. 2003;42:1215-1218.
14
Heitmiller RF, Labs JD, Lipsett PA. Vagal schwannoma. Ann Thorac Surg 1990;50:811-813.
15
Ayub S, Shakoor MT, Hasan S, et al. Mediastinal mass diagnosed as a benign schwannoma. Singapore Med J. 2011;52:e167-e169.
16
AndersenDB, Kamp S, Madelung A, et al. Unilateral hyperhidrosis and hypothermia: symptoms of an intrathoracic tumour. British Journal of Dermatology. 2015;74:1147-1148.
17
Kato M, Shioata S, Shiga K, et al. Benign Giant Mediastinal Schwannoma Presenting as Cardiac Tamponade in a Woman: A Case Report. J Med Case Rep. 2011;14:5:61.
18
Kitamura Y, Sakakura N, Uchida T, et al. Neurinoma Arising From Brachial Plexus With Intrathoracic Extension Resected Through the Second Intercostal Space. Kyobu Geka. 2010;63:1133-1135.
19
Gossot D, Izquierdo RR, Girard P, Stern JB, Magdeleinat P. Thoracoscopic resection of bulky intrathoracic benign lesions. Eur J Cardiothorac Surg. 2007;32:848-851.
20
Kan P, Schmidt MH. Minimally invasive thoracoscopic resection of paraspinal neurogenic tumors: technical case report. Neurosurgery. 2008;63:54.
21
Yamaguchi M, Yoshino I, Kameyama T, et al. Thoracoscopic surgery combined with a supraclavicular approach for removing a cervico-mediastinal neurogenic tumor: a case report. Ann Thorac Cardiovasc Surg. 2006;12:194-196.
22
Endo S, Murayama F, Otani S, et al. Alternative surgical approaches for apical neurinomas: a thoracoscopic approach. Ann Thorac Surg. 2005;80:295-298.
23
Landreneau RJ, Dowling RD, Ferson PF. Thoracoscopic resection of a posterior mediastinal neurogenic tumor. Chest. 1992;102:1288-1290.
24
Sakumoto N, Inafuku S, Shimoji H, et al. Videothoracoscopic surgery for thoracic neurogenic tumors: a 7-year experience. Surg Today. 2000;30:974-977.