ÖZET

Amaç:

Koronavirüs hastalığı-2019 (COVID-19), Aralık 2019’dan bu yana sağlık hizmetlerinin ana uğraşı haline gelmiş bir hastalıktır. Hematoloji hastalarının COVID-19 tedavi ve takiplerinde zorluklar yaşanmaktadır. Bu çalışmada COVID-19 tanısı alan hematolojik hastaların hastalık seyri ve ölüm oranlarına ilişkin verileri paylaşmayı amaçladık.

Gereç ve Yöntem:

Mart 2020 ile Şubat 2021 arasında COVID-19 tanısı konulan hastalar çalışmaya dahil edildi. Hastalar retrospektif olarak incelendi.

Bulgular:

Kırk dokuz hasta değerlendirildi. Yirmi biri kadın, 28’i erkek idi, ortanca yaş 64 (19-84) idi. On dokuz hastada komorbidite yoktu. Otuz hastada 1-4 ek tanı vardı. Kırk bir (%83) hastada malign hematolojik tanı saptandı, 33’ü (%67) aktif kemoterapi alıyordu. On altı (%33) hasta sitopenik dönemdeydi. Altı hasta tanı anında asemptomatikti. Hastaların 19’u (%38,8) hafif, 6’sı (%12,2) orta derecede COVID-19, 24’ü (%49) ağır hastalığa sahipti. On dört (%29) hasta evde takip edilirken, 35 (%71) hasta hastaneye yatırıldı. Yatan hastaların 21’i (%60) yoğun bakımda takip edildi. Toplam 17 hasta (%34,6) COVID-19 enfeksiyonundan öldü. Hematolojik nedenlerle hastanede yatışı sırasında COVID-19 tanısı almış olmak, hematolojik hastalık durumu, COVID-19 tedavisi için yatış, akciğer tutulumu, eşlik eden ekstrapulmoner organ tutulumu, anemi, trombositopeni, sistemik enflamatuvar yanıt sendromu gelişimi, yoğun bakıma yatış, entübasyon ve sekonder enfeksiyon gelişimi daha yüksek mortalite ile ilişkili bulundu.

Sonuç:

Bu çalışmada, hematolojik hastalarda COVID-19’un daha yüksek morbidite ve mortaliteye sahip olduğunu gözlemledik. Bu nedenle hematolojik hasta gruplarını COVID-19 döneminde hastalıktan korumak için daha fazla özen gösterilmelidir.

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Hematolojik Hastalarda COVID-19 Hastalığı-Tek Merkez Verisi

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References