ABSTRACT

Sinonasal adenocarcinomas (SAs) are local aggressive tumors and occur in middle and advanced aged male patients. A polypoid mass involving to the left nose and paranasal sinuses was determined in endoscopical examination of a 57-year-old female patient admitting with epistaxis. Punch biopsy revealed a low grade adenocarcinoma. The mass was totally excised and its histopathological features were similar to punch biopsy. Glandular epithelium was positive for EMA, CK7, CK19, LMWCK and S-100. The findings were concordant with a low grade adenocarcinoma originating from sinonasal mu-cosa. No recurrence was determined 20 months after total excision. SAs are a heterogenous group of neoplasms characterizing by variable clinical behavior and dif-ferent epidemiological features. In the differential diagnosis, many tumoral and tumor like lesions should be considered. The differential diagnosis is very important because of the risk of recur-rence.