ABSTRACT

We aimed to search the relation between androgenetic alopecia (AGA) and cardiovascular atherosclerosis measured via carotid intima-media thickness (CIMT) and the SYNTAX score.

One hundred and sixteen subjects with an indication for coronary angiography were prospectively enrolled into the study. AGA was classified according to the Hamilton baldness scale (for males) and Ludwig scale (for females). Subjects were separated into three groups according to degree of their baldness scale. The SYNTAX score and CIMT were measured for each subject accordingly. Analyses of male and female subjects were carried out separately.

For male subjects; group 3 (n=15) had significantly higher SYNTAX score compared to group 1 (n=14) and group 2 (n=35). Similarly for female subjects, group 3 (n=12) had significantly higher SYNTAX score compared to group 1 (n=29) and group 2 (n=14). Among both male and female subjects, CIMT of group 3 were significantly higher than that of other groups.

AGA may be a simple phenotypical indicator for cardiovascular atherosclerosis since we found that patients with higher stage of AGA had significantly higher SYNTAX score and CIMT value among both gender.

Keywords: Androgenetic Alopecia; Atherosclerosis; Carotid Intima-Media Thickness; the SYNTAX Score