ABSTRACT

Familial Mediterranean fever is the most common in the hereditary periodic fever syndromes. The frequency of vasculitis syndromes are high in familial Mediterranean fever population. Protracted febrile myalgia syndrome is an familial Mediterranean fever-specific manifestation. This syndrome is characterized by severe myalgia, protracted high fever, increased erythrocyte sedimentation rate, hypergammaglobulinemia, normal creatine phosphokinase, and nonspecific inflammatory myopat-hic changes on electromyography. In this letter, we reported a case of familial Mediterranean fever presenting with protracted febrile myalgia syndrome as dramatically responsive steroid therapy.