“Direct acting antivirals” cure over 99% in the course of the disease as a recent breakthrough treatment method in hepatitis C treatment. Possible drug-drug interactions should not be overlooked. In this case report we aimed to share how we managed the interaction in a patient who was planned to use sofosbuvir-ledipasvir. The use of direct antiviral drugs is a very important point in Hepatitis C treatment. A good patient history and a multidisciplinary approach are necessary for the interaction of drugs. These are necessary for successful and safe treatment of hepatitis C.
Keywords: Antiviral Treatment, Hepatitis C, Drug-drug Interactions