Scrotal calcinosis (SC) is a benign disease characterized by multiple calcified nodules localized in scrotal dermis. Scrotal nodules develope slowly over many years and patients usually do not seek for treatment, until they care about their appearance. Histopathologic evaluation reveals multiple calcified nodules surrounded by a chronic granulomatous reaction including histiocytic giant cells. Numerous theories have been reported regarding the possible etiology of SC; the most popular ones including dystrophic calcification of preexisting epithelial cysts and purely idiopathic origin. We report a case of 51 years old man with a rapid onset and spreading scrotal nodules in a period of three months, and discuss whether SC is idopathic or not. We observed three epithelial cysts and a calcified nodule with partially epithelial lining. Our findings support the theory that SC is the result of the calcification of preexisting epithelial cysts. We think that histopathological findings vary with the age of the cysts, and there might be a repetitious cause which leads to new developing active lesions. It is not surprising that because the lesions survive for many years and the treatment is usu-ally performed at late stages, lesions could not demonstrate epithelial component until there is a newly developing cyst.
Keywords: Calcification,Calcinosis,Dystrophic,Scrotum
