Research Article

Clinical Features of Pseudotumour Cerebri Syndrome Syndrome: A Retrospective Evaluation of 60 Patients


  • Yasemin Eren

Received Date: 30.11.2018 Accepted Date: 04.03.2019 J Ankara Univ Fac Med 2019;72(1):61-65


To evaluate the demographic, clinical and radiological characteristics of the patients who are followed up with the diagnosis of pseudotumour cerebri syndrome (PTCS).

Materials and Methods:

The etiological, symptomatic, ophtalmologic, radiological and treatment data of sixty cases that were followed up at the outpatient headache clinic between 2014 and 2018 were retrospectively analyzed.


Fifty-four female patients having an average age of (36.50±12.37) and 6 male patients having an average age of (33.70±9.17) were included in the study. Mean disease period was 8.91±12.73 months and mean body mass index value was 30.43±5.27. Etiologically, it was due to primary (73.3%) or secondary (26.7%) causes. Headache was present in 91.7% of the patients, tinnitus in 65%, diplopia in 16.7% and papiloedema was present in all the patients. In magnetic resonance imaging, extension of the perioptic subarachnoid space was observed in 26 patients, flattening in the posterior globe in 3 patients, Arnold-Chiari malformation in 1 patient, and empty sella in 9 patients. In the treatment, 43 patients used acetazolamide, 13 patients used acetazolamide and topiramate, 2 patients used acetazolamide, furosemide and topiramate, and 1 patient used topiramate. Optic nerve fenestration was applied to 1 patient.


Update of the clinical and neuroimaging findings has brought a more detailed approach for the PTCS diagnosis. However, the pathophysiology of PTSS remains unclear. Researches on this regard will enable the development of more effective diagnosis and treatment methods.

Keywords: Idiopathic Intracranial Hypertension, Pseudotumour Cerebri Syndrome, Headache

Full Text (Turkish)